Key Point: IV to PO conversions benefit both the patient and the healthcare facility. In addition, a system in place to identify eligible patients is an CMS requirement. Key Point: Antibiotic Stewardship Committee identified these broad-spectrum antibiotics as eligible for IV to PO conversion. How do I perform IV to PO conversion? Enalaprilat is the active metabolite of the oral prodrug enalapril maleate. Enalaprilat is poorly absorbed orally and must be administered intravenously. It inhibits angiotensin I to angiotensin II conversion via competitive inhibition of enzyme (ACE). This inhibition disrupts the renin-angiotensin-aldosterone system.
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