• Insulin to detemir conversion

    If from insulin glargine to LEVEMIR, the change can be done on a unit-to-unit basis. • If from NPH insulin, the change can be done on a unit-to-unit basis. However, some patients with type 2 diabetes mellitus may require more LEVEMIR than NPH insulin, as observed in one trial [see Clinical Studies (14)]/ Consider Tresiba®, another basal insulin injection, to your patients 1 year of age and older with diabetes. The dose conversion is easy and Tresiba® utilizes the same FlexTouch® pen as Levemir®. Read important safety & info on this page. x Detemir has a dose conversion to glargine. from 70/30 or other premixed insulins to glargine/ aspart regimen: x Calculate total daily dose of insulin received from 70/30 or other premixed insulin. Insulin detemir is distributed more slowly to peripheral target tissues since insulin detemir in the bloodstream is highly bound to albumin. For doses in the interval of to U/kg, LEVEMIR exerts more than 50% of its maximum effect from 3 to 4 hours up . Insulin glargine (Toujeo) to insulin glargine (Lantus) or insulin detemir (Levemir)  Reduce dose by about 20% when to Lantus17to be conservative.  No info specific to Levemir; consider 20% dose reduction to be conservative. NPH or to ultra-long Size: KB. Lantus is composed of dissolved glargine (a synthetic derivative of human insulin), while Levemir contains dissolved detemir. While they both provide (12 to 24 hour) insulin, they deliver insulin throughout the bloodstream in different ways. BASAL INSULIN ANALOGS: Levemir® (detemir) Lantus®, Basalgar® (glargine U) Toujeo® (glargine U) Tresiba® (degludec U & U) Interchange Recommendations: Basal insulin analogs may be interchanged with NPH with a 20% reduction in . Oct 30,  · NPH to Levemir (Insulin Detemir) When from an NPH to an insulin detemir product like Levemir, conversions should be made unit-per-unit. However, it is possible that some patients on basal-bolus insulin may require more Levemir than NPH. The dose of Levemir should be administered once daily or divided twice daily for additional control. Conversion from Other Insulin Therapies: Insulin glargine and NPH insulin can be converted on a unit to unit basis; closely monitor blood glucose the transition and in the initial weeks thereafter, the dose and frequency of insulin may need to be adjusted/
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