Results. After adjustment for potential confounders such as the comorbidities of schizophrenia, major depression, bipolar disorder, anxiety, insomnia, substance use, and other mental disorders, the Charlson comorbidity index, and use of or antidepressants, zolpidem exposure was found to be significantly associated with the risk of suicide/suicide attempt with an OR of (95% Cited by: Lethal doses of zolpidem are dependent on several factors, such as the person’s body weight, their tolerance level to the drug, their gender, and the use of any other drugs in conjunction with Ambien. amounts of the drug greater than mg of zolpidem per kilogram of an individual’s body weight is most likely to be fatal.
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