How Long Does Hydrocodone Stay in Your System? Naturally, in order to get out of the system, the first step is that you must discontinue it. Unfortunately, when a person stops hydrocodone, it can cause a number of withdrawal symptoms that anyone it should be aware of. Aug 28, · Prospective clients treatment for drug or alcohol addiction opioid dependence often want to know how long it will take for a particular drug to leave their system. In the case of opiates, a class of drugs derived from the poppy plant, opiate withdrawal symptoms and timelines can vary based on a number of factors.
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